Advance article alerts. New issue alert. Receive exclusive offers and updates from Oxford Academic. Have the Pteroylpolyglutamates a Regulatory Function? Short-Term Regulation of Urea Synthesis. Related articles in PubMed Methylmercury chronic exposure affects the expression of DNA single-strand break repair genes, induces oxidative stress, and chromosomal abnormalities in young dyslipidemic APOE knockout mice.
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Nutritional screening tool for critically ill children: a systematic review. Efficacy and tolerability of the ketogenic diet and its variations for preventing migraine in adolescents and adults: a systematic review. Contact a health care provider if you have questions about your health. Arginase deficiency. From Genetics Home Reference. Description Arginase deficiency is an inherited disorder that causes the amino acid arginine a building block of proteins and ammonia to accumulate gradually in the blood.
Frequency Arginase deficiency is a very rare disorder; it has been estimated to occur once in every , to 1,, individuals. Causes Mutations in the ARG1 gene cause arginase deficiency. Learn more about the gene associated with Arginase deficiency ARG1. Inheritance This condition is inherited in an autosomal recessive pattern , which means both copies of the gene in each cell have mutations.
Research Studies from ClinicalTrials. Urea Cycle Disorders Overview. Hyperargininemia due to liver arginase deficiency. Mol Genet Metab. Epub Dec Here, we showed for the first time that arginine supplementation decreases both ammonemia and the lymphocyte response during intense exercise and that the use of this amino acid can be a strategy to modify metabolism during exercise. Br J Sports Med. Article Google Scholar. Immunol Today. Physiol Rev. Gleeson M: Immune function in sport and exercise.
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Cell Biochem Funct. Med Sci Sports Exerc. Cameron LC: Mass spectrometry imaging: facts and perspectives from a non-mass spectrometrist point of view. J Nutr. Scand J Med Sci Sports. Nieman DC: Exercise, infection, and immunity. Eur J Appl Physiol. Can J Physiol Pharmacol. J Immunol. Nat Med. J Neuroimmunol. Kipnis J, Cohen H, Cardon M, Ziv Y, Schwartz M: T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions.
Download references. We wish to thank Dr. Mazon for his professional support during the performance of the tests and Dr. University Castelo Branco, Av. Salvador Allende 6. You can also search for this author in PubMed Google Scholar. Correspondence to Luiz-Claudio Cameron. All authors read and approved the final manuscript. Reprints and Permissions. A sportomics strategy to analyze the ability of arginine to modulate both ammonia and lymphocyte levels in blood after high-intensity exercise.
J Int Soc Sports Nutr 9, 30 Download citation. Received : 10 October Accepted : 13 June Published : 26 June Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article.
Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. Download PDF. Abstract Background Exercise is an excellent tool to study the interactions between metabolic stress and the immune system. Conclusions These data indicate that increases in lymphocytes and ammonia are simultaneously reduced by arginine supplementation.
Background We previously proposed that exercise can be used as a tool to study the interactions between metabolic stress and the immune system[ 1 , 2 ]. Diet Athletes from both groups followed a low-carbohydrate diet LCD as previously described[ 16 ]. Experiment The participants engaged in a six-minute Brazilian Jiu-Jitsu match in full gear. Results Proteins and injury markers To ensure that the athletes were at similar training levels and had similar liver integrities, we measured the classic muscle and liver injury markers.
Figure 1. Full size image. Figure 2. Figure 3. Figure 4. Figure 5. Figure 6. Figure 7. Discussion Ammonia has deleterious effects on many systems, including the CNS, and has been identified as a potential cause of central fatigue. Conclusions The modulation of arginine through supplementation in exercise is well established. References 1. Article Google Scholar 2.
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